University of Queensland researchers have used super-resolution microscopy to observe key molecules at work inside living brain cells, further unraveling the puzzle of memory formation and the elusive causes of dementia. UQ Queensland Brain Institute's Clem Jones Centre for Ageing and Dementia Research Professors Frédéric Meunier and Jürgen Götz found a protein, Tau, involved in Alzheimer's disease affects the organization of the signaling protein Fyn, which plays a critical role in memory formation.
Biomedical researchers at KU Leuven have found a new way to study endometrial diseases such as endometriosis and cancer. They were able to grow three-dimensional cell structures from diseased tissue of patients. The biobank can be used to unravel the disorders and test drugs.
Researchers at Worcester Polytechnic Institute (WPI) have developed a chip made of carbon nanotubes that can capture circulating tumor cells (CTCs) of all sizes and types and can do so with far greater sensitivity than existing technologies. The unique design of the device makes it possible to easily identify and even culture the captured cells, which could make it possible to detect early-stage tumors, predict the course of cancer, and monitor the effects of therapy.
(July 26, 2019) The vast majority of deadly lung cancer cases (85 percent) are termed non-small-cell lung carcinomas (NSCLCs), which often contain a mutated gene called LKB1. Salk Institute researchers have now discovered precisely why inactive LKB1 results in cancer development. The surprising results, published in the online version of Cancer Discovery on July 26, 2019, highlight how LBK1 communicates with two enzymes that suppress inflammation in addition to cell growth, to block tumor growth. The findings could lead to new therapies for NSCLC.
Although psychiatric disorders can be linked to particular genes, the brain regions and mechanisms underlying particular disorders are not well-understood. Mutations or deletions of the SHANK3 gene are strongly associated with autism spectrum disorder (ASD) and a related rare disorder called Phelan-McDermid syndrome.
The human body is an immensely complex system of biological components, containing over 200 different types of cells that make up our organs, bones, muscles, nerves and beyond.
Finnish company Solar Foods is in the process of bringing a new type of protein to the market, and they're creating it out of thin air.
Scientists at The Institute of Cancer Research (ICR) in London believe they have found a way to detect men most likely to develop prostate cancer through genetic testing. According to their recent study, tests for genetic weaknesses in DNA repair genes could identify those that could benefit most from new, highly targeted nuclear "search-and-destroy" medicine.
Targeting medical treatment to an ailing body part is a practice as old as medicine itself. A Band-Aid is placed on a skinned knee. Drops go into itchy eyes. A broken arm goes into a cast.
A novel sensor designed by MIT researchers could dramatically accelerate the process of diagnosing sepsis, a leading cause of death in U.S. hospitals that kills nearly 250,000 patients annually.
Scientists can turn proteins into never-ending patterns that look like flowers, trees or snowflakes, a technique that could help engineer a filter for tainted water and human tissues.
Researchers at Tel Aviv University, led by Prof. Carmit Levy and Dr. Tamar Golan of the Department of Human Genetics and Biochemistry at TAU's Sackler School of Medicine, have discovered that fat cells are involved in the transformation that melanoma cells undergo from cancer cells of limited growth in the epidermis to lethal metastatic cells attacking patients' vital organs.
Epileptic seizures happen in one of every 10 people who have experienced a traumatic brain injury (TBI). However, new research at The University of Texas at San Antonio (UTSA) has uncovered an innovative approach to possibly slow the progression of epilepsy.
Herbs, including cilantro, have a long history of use as folk medicine anticonvulsants. Until now, many of the underlying mechanisms of how the herbs worked remained unknown. In a new study, researchers uncovered the molecular action that enables cilantro to effectively delay certain seizures common in epilepsy and other diseases.