naturewn.com

Trending Topics men women female brain stress

Pathogenic, drug-resistant bacteria found in wastewater treatment plants

Mar 22, 2019 09:15 AM EDT
Close
Wastewater Settlement Tank (IMAGE)
This is a wastewater settlement tank.


(Photo : Theo Gouliouris)

Infections caused by drug-resistant bacteria are a global public health threat causing serious illness and even death. Strains of the bacterium Enterococcus faecium (E. faecium) are generally harmless in healthy people, but can be pathogenic in immunocompromised or severely ill patients. E. faecium strains from hospital environments have acquired resistance to commonly used antibiotics, including those used to treat serious infections, making these infections especially challenging to treat.

In a study published today in Genome Research, researchers conducted a survey of 20 municipal wastewater plants in England, and isolated drug-resistant E. faecium from all sites in both untreated and treated wastewater plants except three, which use ultraviolet light disinfection. Importantly, drug-resistant E. faecium counts were significantly higher in untreated wastewater from plants that were direct recipients of hospital sewage. A genomic comparison of E. faecium isolates from wastewater and bloodstream isolates of infected patients revealed two major lineages, with ampicillin-resistant bacteria in clade A1 and A2 and vancomycin-resistant bacteria exclusive to clade A1. Further genetic analysis revealed the presence of shared antibiotic, metal, and biocide resistance genes in clade A1 isolates from bloodstream, hospital sewage, and municipal wastewater.

This study demonstrates close genetic relatedness of drug-resistant E. faecium isolates released into the environment with those that cause serious human disease. Further research is needed to determine the public health implications of exposure to healthcare- and waste-associated pathogens. Terminal ultraviolet light disinfection of wastewater is one solution that would reduce environmental contamination with drug-resistant bacteria.

© 2018 NatureWorldNews.com All rights reserved. Do not reproduce without permission.

Join the Conversation

arrow
Email Newsletter
About Us Contact Us Privacy Policy Terms&Conditions
Real Time Analytics